abstract |
The present invention provides a pharmaceutical composition for treating gastrointestinal diseases using ranitidine, sucralfate, and bismuth subcitrate as an active ingredient, and a method for producing the same. According to the present invention, in the preparation of a combination of ranitidine, sucralfate and bismuth subcitrate, the problem of hygroscopicity of ranitidine is solved by controlling the particle size of sucralate and bismuth subcitrate, and at the same time, the stability of the preparation and the bioavailability . |