http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101578494-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-64 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-08 |
| filingDate | 2014-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101578494-B1 |
| titleOfInvention | Antiaging cosmetic composition containing cell-transducible carbonyl fusion protein and pozzolan |
| abstract | Human Carbonyl Reductase 1 (CBR1) is a member of the NADPH-dependent short chain dehydrogenase / reductase superfamily, which is known to play an important role in nerve cell survival through antioxidant function. The present inventors prepared a cell permeable PEP-1-CBR1 fusion protein, and examined whether it exhibited protection against inflammation and apoptosis induced by LPS or hydrogen peroxide by permeating into cells and tissues. As a result, the PEP-1-CBR1 fusion protein effectively permeated into HaCaT cells and showed remarkable cytoprotective action against hydrogen peroxide induced inflammation and apoptosis. In addition, the pre - treatment of pozzolan showed a superior protective effect against apoptosis mechanism. PEP-1-CBR1 fusion protein and pozzolan are available as antioxidant functional cosmetics. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200052773-A |
| priorityDate | 2014-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 420.