http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101577315-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 |
| filingDate | 2014-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101577315-B1 |
| titleOfInvention | Methods for Screening Therapeutics for Cancer Using Interaction between AIMP2-DX2 and p14/ARF |
| abstract | More particularly, the present invention relates to a method for screening cancer therapeutic agents using the interaction of AIMP2-DX2 and p14 / ARF, and more particularly, to a method for screening cancer therapeutic agents using AIMP2-DX2 and p14 / Or a fragment thereof; And (b) determining whether the test substance inhibits the interaction of the AIMP2-DX2 protein or a fragment thereof and the p14 / ARF protein or a fragment thereof, wherein the test substance An anticancer drug screening inhibiting the interaction of p14 / ARF with AIMP2-DX2, comprising the step of selecting the test substance as the first candidate substance when the interaction of AIMP2-DX2 and p14 / ARF is reduced in contact with the substance The present invention also relates to a pharmaceutical composition for treating cancer comprising a substance screened by the screening method as an active ingredient. AIMP2-DX2 protein and p14 / ARF protein, which is effective for screening anticancer agents to produce anticancer agents. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11442057-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102297505-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20170104263-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017155277-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109073638-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019512693-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109073638-A |
| priorityDate | 2013-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 454.