http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101572315-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-9015 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y603-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 |
filingDate | 2013-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2015-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101572315-B1 |
titleOfInvention | Method for screening modulator of RIG-I mediated immune response via stabilization of MARCH5 expression |
abstract | The present invention relates to a method of screening for an RIG-I mediated immune response modulating agent through stabilization of mitochondrial E3 ubiquitin ligase (MARCH5) expression, which comprises (1) mitochondrial E3 ubiquitin ligase (MARCH5) ≪ / RTI > constructing an expressing cell line; (2) contacting the test substance with the cell line constructed in the step (1) and measuring the degree of MARCH5 expression; (3) expressing the RIG-I protein in the cell line constructed in the step (1) and measuring the degree of MARCH5 expression; And (4) selecting a test substance whose expression level of MARCH5 measured in step (2) is higher than that of the control, using the degree of MARCH5 expression measured in step (3) as a control, Screening method. |
priorityDate | 2013-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 105.