| abstract |
The present invention relates to the discovery that certain human taste receptors in the T2R taste receptor family respond to certain bitter compounds, for example, present in coffee. The present invention also relates to the discovery of certain compounds and compositions which function as bitter taste blockers and their use as bitter taste blockers or flavor control agents, for example in coffee and coffee flavored foods, drinks and medicines. The invention also relates to compounds which antagonize a number of different human T2Rs and their use in the analysis and in the compositions ingested by humans and animals as bitter taste blockers. |