abstract |
Disclosed is a polysaccharide gel formulation comprising at least one polysaccharide degradation inhibitor and a process for its preparation. The method includes providing at least one polysaccharide and incorporating at least one degradation inhibitor into the polysaccharide. In some embodiments, the incorporation step comprises 1) mixing the at least one inhibitor with the at least one polysaccharide in a highly hydrated state to encapsulate at least one inhibitor in the polysaccharide network, and 2) dehydrating the polysaccharide network to release kinetics And controlling the final expansion ratio. In another embodiment, the incorporation step comprises: 1) encapsulating at least one inhibitor in a biocompatible or biodegradable vessel, and 2) combining the polysaccharide and vessel in a gel formulation. The disclosed polysaccharide gel formulations can be used in a variety of cosmetic applications. |