abstract |
The present invention relates to tricyclic PI3K inhibitor compounds of formula (I) having anticancer, antiinflammatory, or immunoregulatory properties, more particularly PI3 kinase control or inhibitory activity. The invention also relates to methods of using tricyclic PI3K inhibitor compounds of formula (I) for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, organs, or related pathological conditions. The compounds of formula I include the stereoisomers, geometric isomers, tautomers, and pharmaceutically acceptable salts thereof: (I) In this formula, The dotted line represents an optional double bond, the at least one dotted line represents a double bond; Substituents are as described herein. |