http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101546485-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-60 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6809 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4711 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate | 2013-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101546485-B1 |
| titleOfInvention | A pair of amino acid sequences for monitoring tau-tau interaction in living cells via bimolecular fluorescence complementation |
| abstract | The present invention relates to a method for monitoring the interaction between a tau protein in a living cell, a protein sequence for monitoring the interaction between the tau protein, a base sequence pair encoding the same, a vector pair comprising the same, a cell line transformed with the vector pair, The present invention relates to a method for monitoring Tau-Tau interactions in cells, more particularly, to a method for monitoring the interaction of intracellular tau proteins with a bimolecular fluorescent complementary amino acid sequence pair, A first fluorescent complementary amino acid sequence to which an N-terminal sequence of a Venus amino acid sequence is linked; And a second fluorescent complementary amino acid sequence comprising a C-terminal sequence of the Venus amino acid sequence at the C-terminus of the full-length human tauro amino acid sequence, a pair of base sequences encoding the same, A cell line transformed by the vector pair, and a method for monitoring Tau-Tau interaction in living cells using the cell line. According to the present invention, it is possible to monitor and quantify the tau oligomerization process by directly visualizing the Tau-Tau interaction in living cells, thus studying the occurrence of the disease that tau is involved in and the oligomerization process It can be used as a useful means for developing a method for preventing and restoring the data. |
| priorityDate | 2013-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 464.