| abstract |
There is provided a method of synthesizing an influenza virus-like particle (VLP) in a plant or part of a plant. This method involves the expression of influenza HA in plants and purification by size exclusion chromatography. The present invention also relates to a VLP comprising an influenza HA protein and a plant lipid. The invention also relates to nucleic acids and vectors encoding influenza HA. This VLP can be used to produce an influenza vaccine, or to add to an existing vaccine. |