http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101530278-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a251ae79dd7a008d95010b238c6aa1f8 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2200-326 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-235 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-235 |
| filingDate | 2014-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f7a290b1c1e6b6982feff045945418c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e7baf7bda325e0d010a58c786aa1d06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe6d3966c884f12d2e5a0d3d4c65b6f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_167af8faf84b7262d42cf73f5db016aa |
| publicationDate | 2015-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101530278-B1 |
| titleOfInvention | Pharmaceutical Compositon for ischemic heart diseases Comprising AAV including Cardiomyocytes Converson Factors and Cardiovascular Regenerative Gene |
| abstract | The present invention relates to a composition for preventing or treating ischemic heart disease, which comprises an adeno-associated virus comprising a myocardial transformation gene and a cardiovascular regeneration gene as an active ingredient. More specifically, the present invention relates to a composition for the prevention or treatment of ischemic heart disease comprising, as an active ingredient, adeno-associated virus inserted with Gata4, Mef2c, Tbx5, and cardiovascular regenerating gene Thymosin? The composition according to the present invention uses Gata4, Mef2c, Tbx5 (GMT) directly transforming fibroblasts into cardiomyocytes as a functional gene candidate using clinically relevant adeno-associated virus, And Thymosin beta4 (hereinafter, referred to as T? 4), which is a gene for promoting blood vessel regeneration and differentiation and myocardial regeneration, are applied to ischemic diseases, thereby directly converting cells in the myocardial infarction area wrapped in fibroblasts and extracellular matrix into myocardial cells, Regeneration and myocardial regeneration-related cells to induce cardiovascular regeneration. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019162356-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2571704-A |
| priorityDate | 2014-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 156.