| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_265fe294e7f0996c5d8ee264d3a392b6 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-436
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-436 |
| filingDate |
2013-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2015-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55b39af0c1c33d74c4971aca026abb06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43ecb21ac58a865e80bf598896dffaf5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0a5e6355b661e3f17c89a62ed9a3c60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3addb4a46ed23815caadc3b2deee1607
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_228d691131850354303d187fc2af6d8a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84ccef0692e2b91eed4564ceeeda878f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45eccf5921c8b3c2797ae4a8122b2265 |
| publicationDate |
2015-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-101529963-B1 |
| titleOfInvention |
Method for preparing everolimus and its intermediates |
| abstract |
The present invention relates to a process for the preparation of Eberorimus and its intermediates, and more particularly to a process for preparing Eberorimus by reacting rapamycin of the following formula (3) with 2- (trityloxy) ethyltrifluoromethane sulfonate to obtain a compound of the formula Step 1 to manufacture; And a second step of deprotecting the compound of formula (2) to prepare elloperidus of the following formula (1), thereby producing a high yield of everolimus by an easy and simple method compared to the prior art, and an intermediate thereof will be. [Chemical Formula 1] (2) (Wherein R < 1 > is triphenylmethane) (3) |
| priorityDate |
2013-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |