Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-36 |
filingDate |
2008-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2015-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2015-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-101521674-B1 |
titleOfInvention |
Double-stranded polyethylene glycol modified growth hormone, preparation method and application thereof |
abstract |
The present invention provides a growth hormone (GH) exhibiting high biological activity modulated by a double-stranded polyethylene glycol at a single site, and a method of producing the same. PEG-attached GH exhibits higher biological activity and longer half-life than normal GH. Compositions comprising PEG-attached GH are useful in the treatment of growth or developmental disorders, such as GH deficiency, Turner's syndrome, and the like. |
priorityDate |
2008-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |