http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101515066-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0325 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-108 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2015-8563 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-025 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-02 |
filingDate | 2011-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2015-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101515066-B1 |
titleOfInvention | Genetically-modified cell line for inhibiting blood coagulation for xenotransplantation and method for preparing the same |
abstract | The present invention relates to a cell line overexpressing a gene vector for preventing blood coagulation for heterologous organs, and a method for producing the same. More specifically, the present invention relates to a cell line inhibiting blood clotting, The hTFPI? And hCD39 overexpressed hTFPI? And hCD39, which were transfected with the vector regulated by the ICAM2 promoter and the MCP promoter, were transfected with hTFPI? And hCD39. The transgenic mini-pigs transfected with hTFPI? , It is possible to effectively suppress the thrombosis and coagulopathy which are a major part of the humoral immune rejection reaction after overcoming the immune rejection response, . |
priorityDate | 2011-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 109.