| abstract |
Methods for the synthesis of chelator-targeted ligand conjugates, compositions comprising such conjugates, therapeutic and diagnostic applications of such conjugates are described herein. The composition optionally comprises a chelator-targeted ligand conjugate chelated to one or more metal ions. A method of synthesizing these compositions in high purity is also presented. Also described are methods of imaging, treating and diagnosing diseases in a subject using these new compositions, for example, imaging tumors in a subject and methods of diagnosing myocardial ischemia.n n n Chelator, target, ligand, conjugate, imaging, diagnosis, treatment. |