| abstract |
The present invention relates to the treatment of eye diseases and conditions by administering a complement pathway inhibitor, particularly an alternative pathway inhibitor. Eye diseases include senile macular degeneration, diabetic retinopathy, and neovascularization of the eye. One embodiment involves the administration of anti-factor D antibodies in the form of whole antibodies, Fab fragments or single domain antibodies. Other complement component inhibitors that may be useful in the methods of the present invention include inhibitors that block the action of Factor H or Propeldine, Factor B, Factor Ba, Factor Bb, C2, C2a, C3a, C5, C5a, C5b, C7, C8, C9, or C5b-9.n n n Eye disease, complement pathway, inhibitor, alternative pathway inhibitor, antibody, factor D |