http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101504912-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-747 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-135 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-74 |
| filingDate | 2013-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101504912-B1 |
| titleOfInvention | The products containing probiotic lactobacillus acidophilus HY7037 having activity preventing from insulin resistance, which caused type 2 diabetes mellitus |
| abstract | The present invention relates to a product containing as Lactobacillus ash FIG filler's (Lactobacillus acidophilus) and HY7037 active ingredients it has the effect of improving insulin resistance, Lactobacillus ash FIG filler's (Lactobacillus acidophilus) HY7037 according to the present invention is TNF- α increased the glucose uptake decreased by TNF-α primarily in rat L6 skeletal muscle cells induced by insulin resistance, and the GLUT4 gene involved in glucose uptake Increases protein expression and increases protein phosphorylation of the insulin signal pathway AKT, IRS (Tyr) -1, which affects translocation and expression of GLUT4, and is involved in insulin sensitivity (1) and (2). In addition, the expression of PPARγ and PGC-1α is known to increase the insulin resistance inducing environment, and inflammatory cytokines A pharmaceutical composition for the prevention and treatment of metabolic syndrome by improving the insulin resistance environment which is a main cause of type 2 diabetes by reducing the gene expression level of IL-6 increased by TNF-a, Beverages, fermented products, and the like. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021066549-A1 |
| priorityDate | 2013-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 522.