http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101493882-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-167 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 |
| filingDate | 2013-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101493882-B1 |
| titleOfInvention | Novel heteroarylcarboxamide derivative or pharmacutically acceptable salt thereof, process for the preparation thereof and pharmaceutical composition for prevention or treatment of RAGE receptor related diseases containing the same as an active ingredient |
| abstract | The present invention relates to a novel heteroarylcarboxamide derivative or a pharmaceutically acceptable salt thereof, a process for producing the same, and a pharmaceutical composition for preventing or treating RAGE receptor or acetylcholinesterase activity-related diseases comprising the same. The heteroaryl carboxamide derivative compound of the present invention antagonizes the RAGE receptor, thereby inhibiting the transfer of beta amyloid that binds to the RAGE receptor to the brain by the loss of nerve cells, resulting in excessive accumulation of beta amyloid The effect of inhibiting plaque formation is excellent. In addition, since it is excellent in inhibiting acetylcholinesterase that degrades acetylcholine, which is an important chemical substance in memory function, it is useful for treating RAGE receptor or acetylcholinesterase related diseases such as Alzheimer's disease, cerebrovascular dementia, Dementia including Alzheimer's disease and multiple infarct dementia or dementia including Alcoholic dementia, Pick disease, Creutzfeldt-jakob disease, hypothyroidism, head injury, Parkinson's disease Parkinson's disease, Huntington's disease, and the like. |
| priorityDate | 2013-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 514.