http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101493168-B1
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2121-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-409 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0071 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-409 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2013-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2015-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101493168-B1 |
titleOfInvention | pH sensitive conjugates for photodynamic therapy having nano-pin structure and method thereof |
abstract | The present invention relates to a nano-pin junction for pH-sensitive photodynamic therapy and a method for producing the same. The present invention provides a conjugate for the treatment of pH-sensitive photodynamic therapy in the form of nanopin and a method for producing the same, comprising a photosensitive peptide comprising chlorine Ce6, CKKKKKK amino acid sequence and 2,3- , 3-dimethylmaleic anhydride), a process for preparing the same, and a pharmaceutical composition for photodynamic therapy comprising the conjugate. The nano-pin type pH-sensitive photodynamic therapy conjugate according to the present invention can change the structure of a molecule in response to a disease site having an acidic environment such as cancer, and has a targeting ability to a disease site and a drug accumulation It is possible to maximize the ability and to avoid various immune mechanisms in vivo by using biocompatible polymers and peptides, so that there is an effect of not causing side effects due to non-regulation of immune response. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101791399-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018234586-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11712473-B2 |
priorityDate | 2013-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 77.