http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101488436-B1

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filingDate 2013-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2015-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-101488436-B1
titleOfInvention Method for Detecting Single Mismatches in DNA Hybridization Events Using Gold Nanoparticles
abstract The present invention relates to a method for detecting a single mismatch in a DNA hybridization reaction using gold nanoparticles, and more particularly, to a method for detecting a mismatch between a DNA probe and a detection probe capable of complementarily binding with a target nucleic acid, The present invention relates to a method for detecting a single base mutation of a target nucleic acid by controlling the reaction, quantitatively analyzing the difference between the absorbance of a complete hybridization of the target nucleic acid and the incompletely hybridized single base mutation. The method for detecting a single base mutation of a target nucleic acid of the present invention quantitatively analyzes a difference in absorbance of a target nucleic acid and a single base mutation through a DNA-DNA hybridization reaction and a salt concentration control process, It is possible to detect a single base mutation and to use early prediction of the risk of a disease such as breast cancer.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023164224-A1
priorityDate 2013-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 32.