| abstract |
The present invention relates to 4-aryl-6-piperazin-1-yl-3-substituted-pyridazines, the racemic dopamine 2 receptor antagonists, to their preparation and to pharmaceutical compositions comprising these compounds as active ingredients . Such compounds have been found to be useful as medicaments for the treatment or prevention of central nervous system disorders, for example, schizophrenia, by exerting an antipsychotic effect without exercise side effects. |