http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101485163-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
filingDate | 2012-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2015-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101485163-B1 |
titleOfInvention | Composition of Regulating Differentiation into Dopaminergic Neurons by ADAM17 |
abstract | The present invention relates to a method for controlling the differentiation of neural stem cells or neural progenitor cells into dopaminergic neurons, comprising the step of increasing or inhibiting the activity of ADAM17 in neural stem cells or neural precursor cells, and a composition for treating cerebral neurological diseases The methods and compositions of the present invention modulate the activity of ADAM17 on neural stem cells or neural progenitor cells to increase dopaminergic neurons in the midbrain region and induce dopaminergic neuronal cell death such as Parkinson's disease And by inhibiting the activity, it is possible to improve the therapeutic effect of a disease such as a tumor. |
priorityDate | 2012-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 167.