| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0215
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-542
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D305-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06 |
| filingDate |
2011-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2014-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-101477194-B1 |
| titleOfInvention |
Chemical synthesis and anti-tumor and anti-metastatic effects of dual functional conjugate |
| abstract |
The present invention relates to the chemical synthesis of a bifunctional complex such as formula (I) and to the antitumor and antitumor metastatic action, and more particularly to a complex formed by taxol or doxetaxol and muramyldipeptide (MDP) derivatives . Taxa or Taxes Taxol and the immune enhancer Mura Mildi Peptide (MDP) are linked to each other, resulting in the heterogeneous efficacy of antitumor and anti-tumor metastasis combined with chemotherapy and immunotherapy. The present invention relates to the synthesis of several taxol or taxa taxol and muramyldipeptide (MDP) simplifying substances by solid phase synthesis and liquid phase synthesis, and also through the reliable biological experiment method and data, Can be used. |
| priorityDate |
2010-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |