Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d0fc2b70675ee19bd5fc464f5ae9061 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-17 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
filingDate |
2014-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1b1be07d39a95d282d7ecb4eb8a8532 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e142a958118d3a06a2458f82f4c0c91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11e1838a19de8e2758a1d27678a679de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8edfbd446110a5228d7c51aa0d55248b |
publicationDate |
2014-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-101473153-B1 |
titleOfInvention |
Novel use of Protein Phosphatase Inhibitor 2 |
abstract |
The present invention provides a novel use of the protein phosphatase inhibitor 2 in the prevention or treatment of degenerative brain diseases. The protein phosphatase inhibitor 2 protein according to the present invention, a polynucleotide encoding the same, or an expression vector comprising the polynucleotide can restore the fragmentation of mitochondria appearing in neurons to a normal level of mitochondria, Can inhibit apoptosis of the cells. Therefore, they can be usefully used for prevention or treatment of degenerative brain diseases including amyotrophic lateral sclerosis, and screening of therapeutic agents. |
priorityDate |
2014-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |