http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101473153-B1

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filingDate 2014-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1b1be07d39a95d282d7ecb4eb8a8532
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publicationDate 2014-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-101473153-B1
titleOfInvention Novel use of Protein Phosphatase Inhibitor 2
abstract The present invention provides a novel use of the protein phosphatase inhibitor 2 in the prevention or treatment of degenerative brain diseases. The protein phosphatase inhibitor 2 protein according to the present invention, a polynucleotide encoding the same, or an expression vector comprising the polynucleotide can restore the fragmentation of mitochondria appearing in neurons to a normal level of mitochondria, Can inhibit apoptosis of the cells. Therefore, they can be usefully used for prevention or treatment of degenerative brain diseases including amyotrophic lateral sclerosis, and screening of therapeutic agents.
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