Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-683 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2527-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-161 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6853 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6851 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6858 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-521 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6818 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-683 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6837 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-52 |
filingDate |
2012-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2014-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-101462192-B1 |
titleOfInvention |
Detection of Target Nucleic Acid Sequence by PTO Cleavage and Extension Assay |
abstract |
The present invention relates to the detection of a target nucleic acid sequence by a PTOCE (PTO Cleavage and Extension) assay. The present invention relates to a method for detecting a probing and tagging oligonucleotide (PTO) hybridized with a target nucleic acid sequence and cleaving a fragment to hybridize to a capturing and template oligonucleotide (CTO) to form an extended duplex, Thereby detecting the target nucleic acid sequence. The extended dimer provides a signal (generation, increase, extinction, or reduction of the signal) from the indicia indicating the presence of the extended dimer and has an adjustable Tm value, which can be applied to the detection of the presence of the target nucleic acid sequence. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023043280-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20160018809-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101863943-B1 |
priorityDate |
2011-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |