http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101460177-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C275-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C335-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C275-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-17 |
| filingDate | 2007-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101460177-B1 |
| titleOfInvention | O-substituted-dibenzylurea-derivatives which are TRPV1 receptor antagonists |
| abstract | The present invention relates to compounds of formula (I) wherein R is selected from halogen, alkyl, alkoxy, aryl and heteroaryl, wherein R 1 is selected from the group consisting of 2-hydroxyethyl, 2,3-dihydroxypropyl, Ethyl, 1,3-dioxane-methyl, 1,3-dioxolane-methyl, 1,3-dioxolane- 2-hydroxypropyl, 3-chloro-2-hydroxypropyl, 2-hydroxypropyl, 2-hydroxy- Benzyl, 4- (hydroxymethyl) benzyl, 4-chlorobenzyl, 4-fluorobenzyl, and 4-hydroxybenzyl from the group consisting of Selected; R 2 is tert-butyl or trifluoromethyl; R < 3 > is independently selected from hydrogen, carboxy, cyano, alkyl or hydroxyalkyl. The compounds of formula (I) are useful for the preparation of pharmaceutical compositions for the treatment of inflammatory conditions such as chronic neuropathic pain, irritable bladder syndrome, tumor pain, dental pulp, inflammatory hyperalgesia, post-operative pain, Lt; / RTI >n n n Vanilloid TRPV1 receptor, inflammation, vanilloid receptor antagonist. |
| priorityDate | 2006-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 130.