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filingDate 2013-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2014-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-101458060-B1
titleOfInvention Bone filling composition comprising caffeic acid phenethyl ester, and manufacturing method thereof
abstract The present invention relates to an antibacterial bone-filling composition and a method for preparing the same, and more particularly, to a caffeic acid ester-containing antibacterial bone-filling composition comprising a caffeic acid phenethyl ester as an active ingredient of propolis, And a method for producing the same. The antibacterial bone-filling composition according to the present invention contains caffeic acid ester, which is an active ingredient of natural antibacterial and anti-inflammatory natural propolis, which has a problem of stability such as return mutation and micronucleus test, It is possible to prevent the generation of fungus which is a factor of secondary infection which occurs at the time of surgery.
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