http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101443581-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2250-0068 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09D133-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G63-91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L33-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F216-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-0077 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F216-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G63-91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L5-10 |
filingDate | 2008-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2014-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101443581-B1 |
titleOfInvention | Coatings for Medical Devices with Antithrombotic Conjugates |
abstract | The present invention relates to a method of producing a comb-like antithrombotic conjugate, wherein substantially all of the side chains of the water-soluble poly (vinyl alcohol) (PVA) are extended by ring-opening polymerization to form a copolymer wherein substantially all of the ends are bonded to the anti- . This method is also provided for preventing or reducing thrombus formation on the device surface by applying a coating comprising a comb-shaped antithrombotic conjugate to at least a portion of the implantable device. The first or sub-layer of the coating is prepared by mixing the polymeric material and the biologically active agent together with a solvent, thereby forming a homogeneous solution. A second or outer layer comprising a comb-like antithrombotic conjugate can be applied over the drug-containing inner layer, for example, using an immersion coating or spray coating process. Alternatively, the comb antithrombotic conjugate can be used as a matrix material to encapsulate a pharmaceutical preparation to form a microcrystalline or nanocomposite before the microcrystalline or nanocomposite is deposited on a medical device.n n n n Antithrombotic conjugate, |
priorityDate | 2007-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 404.