http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101439255-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65616 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-52 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 |
| filingDate | 2012-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101439255-B1 |
| titleOfInvention | The New Tenofovir disoproxil salt and the preparation method thereof |
| abstract | The present invention relates to novel tenofovir disoproxil aspartate compounds. The salt compound can minimize the generation of a flexible substance according to changes over time as compared with the terbinafide disoproxil fumarate salt, so that the stability of the preparation can be improved by greatly reducing the amount of impurities generated during storage of the product containing the salt compound , Eliminating the need to perform separate studies of toxic effects. In addition, since the salt compound of the present invention greatly improves the stability, the wetting property and the solubility according to the pH change and has a physico-chemical property, it can be used for the treatment of HIV-1 infection and chronic hepatitis B together with a pharmaceutically acceptable carrier May be used as an active ingredient of a pharmaceutical composition useful in the present invention. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20180064213-A |
| priorityDate | 2012-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.