http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101434693-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D489-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-08 |
| filingDate | 2007-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101434693-B1 |
| titleOfInvention | Method for producing N-alkylnaltrexone halides |
| abstract | SUMMARY OF THE INVENTIONn n n (i) N-methylnaltrexone methyl sulfate in an aqueous solution is selected from the group consisting of sodium carbonate, potassium carbonate, calcium carbonate, magnesium carbonate, cesium carbonate, strontium carbonate and mixtures thereof such that the pH of the aqueous reaction medium is between 7 and 10 Reacting with an alkaline agent; And (ii) reacting the obtained product with hydrobromic acid added so that the pH of the aqueous reaction medium is from 0.5 to 5 to obtain N-methylnaltrexone bromide. A novel preparation of N-methylnaltrexone bromide ≪ / RTI >n n n N-methylnaltrexone double ion, anhydrous form, hydrate form. |
| priorityDate | 2006-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 15.