http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101430084-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-463 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43563 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
filingDate | 2012-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2014-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101430084-B1 |
titleOfInvention | Novel antibiotic peptide against Propionibacterium acnes and use therof |
abstract | The present invention relates to a pharmaceutical composition for antimicrobial use and an antimicrobial cosmetic composition comprising an antibiotic peptide (HPA3NT3) having antimicrobial activity against Propionibacterium acnes ( P. acnes ) known to cause acne , More specifically glutamine, which is the 16th amino acid of HP (2-20) peptide derived from Helicobacter pylori, and HPA3 peptide, which is an 18th amino acid substituted by tryptophan, The amphipathic antibiotic HPA3NT3 peptide having the amino acid sequence of SEQ ID NO: 3 obtained by cleaving four amino acids at the structurally irregular N-terminal region after substitution of serine with lysine has an antibacterial activity against Propionibacterium acnes, Inhibit the induced erythema, inflammatory response and growth of the strain , IL-8, which is a cytokine, and thus can be effectively used as an active ingredient of a pharmaceutical composition for antimicrobial use and a cosmetic composition for antimicrobial use. |
priorityDate | 2012-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 388.