http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101426873-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2250-21 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-9789 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 |
| filingDate | 2012-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101426873-B1 |
| titleOfInvention | Pharmaceutical composition for prevention and treatment of inflammatory diseases comprising extract or fractions of Ardisia tinctoria Pit. as an active ingredient |
| abstract | The present invention relates to a method for the treatment of Aldisia tinctoria tinctoria The present invention relates to a composition for preventing and treating inflammatory diseases, which comprises extracts or fractions thereof. More particularly, the present invention relates to a composition for inhibiting the production of nitric oxide, which is rapidly increased by inflammation induced by the aldicia tincturea extract or its fractions . The extracts of Aldicia tincturea significantly reduced the levels of PGE 2 and IL-6 (interleukin-6) and IL-1beta cytokines in a concentration-dependent manner and inhibited the expression of iNOS and COX-2 genes and proteins And inhibit nuclear translocation of p65 protein and phosphorylation of signal transducer. Also, it was confirmed that the aldicia tincturea extract and the ethyl acetate fraction had an inflammation-inhibiting effect in the carrageenan-induced mouse foot model. Therefore, the above-mentioned aldicia tincture extract or its fractions can be effectively used as an active ingredient of compositions for preventing or treating inflammation-related diseases, compositions for external application for skin, cosmetic compositions and compositions for health food. |
| priorityDate | 2011-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 203.