http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101423272-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-4893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-08 |
filingDate | 2006-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2014-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101423272-B1 |
titleOfInvention | Compositions and methods for topical and transdermal delivery of botulinum toxin with reduced non-toxin protein |
abstract | The present invention relates to novel compositions of botulinum toxin that can be applied topically for a variety of therapeutic, aesthetic and / or cosmetic purposes. The composition of the present invention is a botulinum toxin complex in which the amount of hemagglutinin, non-toxin non-hemagglutinin and / or exogenous albumin is selectively and independently reduced relative to conventional commercially available botulinum toxin . The compositions of the present invention are non-circular to the botulinum toxin and non-covalently bound to the botulinum toxin complex, acting as a skin-oriented "adhesion molecule" to improve the ability of the toxin complex to adhere to the skin epithelium and penetrate the skin epithelium Lt; / RTI > The compositions of the present invention have an improved safety profile compared to conventional botulinum-containing compositions that are injected subcutaneously. Methods of using such compositions are also contemplated by the present invention.n n n Botulinum, botulinum toxin complex, hemagglutinin. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200121776-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200025608-A |
priorityDate | 2005-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 294.