| abstract |
The present invention is a patch with a stretchable support and a pressure-sensitive adhesive layer laminated on at least one surface of the support, wherein the stretchable support is composed of a woven fabric of double-sided knitted fabrics subjected to crimping and the pressure- And a moisture permeability of 1 to 350 g / m < 2 > 24 hours measured at a temperature of 40 DEG C and a relative humidity of 90% as a whole of the patch preparation, wherein the amount of the pressure sensitive adhesive layer The average value of AUC 0-24 in the plasma of the methyl salicylate is within a range of 3.0 占 퐉 to 3.0 占 퐉 when the patch is applied to human skin for 8 hours so that the contact area becomes 280 cm < 2 > And an average value of AUC 0-24 in the plasma of salicylic acid, which is a metabolite of methyl salicylate, is in the range of 5,000 to 13,000 ng · hr / ml. |