http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101414392-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1271 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4164 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 |
| filingDate | 2007-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101414392-B1 |
| titleOfInvention | Compositions for transfection of oligonucleotides effective for gene silencing and their biological and therapeutic uses |
| abstract | The present invention relates to a transfection composition comprising an oligonucleotide and an amphiphilic cation molecule of the general formula (I)n n n Formula In n n n n n n n [Wherein,n n n X is NR 1, S or O, wherein, R 1 is C 1 ~C 4 alkyl radical or an hydroxylated C 3 ~C 6 alkyl radical;n n n R 2 and R 3 are the same or different and represent H or a C 1 -C 4 alkyl radical or R 2 and R 3 are connected to each other to form a heterocyclic or saturated or unsaturated ring having 5 or 6 elements ;n n n E is a C 1 to C 5 alkyl spacer;n n n R 4 and R 5 are the same or different and represent a saturated or unsaturated linear or branched C 10 to C 36 hydrocarbon or fluorocarbon chain wherein the chain optionally contains C 3 to C 6 cycloalkyl, ;n n n A - is a biocompatible anion.n n n The present invention also relates to a composition effective for delivering an oligonucleotide into a eukaryotic cell in vitro or in vivo in a culture medium. The present invention also relates to a transfection composition comprising an oligonucleotide effective for RNA interference. Such a composition can be used as a means for biological research or as a therapeutic drug. |
| priorityDate | 2006-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.