| abstract |
Pharmaceutical compositions comprising 2S, 4R ketoconazole enantiomers or pharmaceutically acceptable salts, hydrates and solvates thereof that are substantially free of 2R, 4S ketoconazole enantiomers are useful for reducing cortisol synthesis, and for type 2 diabetes , Hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, metabolic syndrome, and other diseases and disorders, including, but not limited to, Cushing's syndrome, depression, and glaucoma. |