http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101377797-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-3955 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-08 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
filingDate | 2012-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2014-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101377797-B1 |
titleOfInvention | Angiogenesis-inhibiting composition containing anti-flt-1 peptide conjugated with mini-PEJ as an active ingredient |
abstract | The present invention can effectively treat diseases caused by abnormal or excessive angiogenesis, such as cancer, rheumatoid arthritis, and 8-amino-3, for the purpose of preventing or treating angiogenic diseases that can enhance the treatment convenience of patients. Angiogenesis-inhibiting composition containing anti-flt-1 peptide conjugated with 6-dioxaoctanoic acid (8-amino-3,6-dioxaoctanoic acid; mini-PEG) as an active ingredient, in particular angiogenesis for oral administration It relates to an inhibitor. The novel D-type mini PEG conjugated anti-flt-1 peptide targeting the vascular endothelial growth factor receptor (VEGFR) -1 (flt-1) according to the present invention targets the existing VEGF or VEGFR. Compared with the drug, it effectively inhibits the binding between vascular endothelial growth factor and its receptor and exhibits almost the same antiangiogenesis effect as parenteral administration. It can be used as a therapeutic agent that can be administered. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017099319-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101644440-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108350029-A |
priorityDate | 2011-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 637.