http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101367896-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-10 |
| filingDate | 2012-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101367896-B1 |
| titleOfInvention | Bone growth active composition comprising MSM as an active ingredient |
| abstract | The present invention relates to a composition for activating bone growth of MSM (methylsulfonylmethane), a method for inducing osteoblast differentiation from mesenchymal stem cells and a composition thereof. The composition of the present invention can regulate or activate Jak2 and STAT5b proteins that mediate the expression of IGF-IR, IGF-1 and GHR genes that contribute to bone growth in osteoblasts (osteoblasts) of humans and animals. And STAT5b-mediated bone growth has the effect of raising the height of growing children. In addition, MSM increased the expression of bone differentiation marker genes along with GH in bone formation and differentiation in mesenchymal stem cells, and has the effect of enhancing mineralization, which is important in the late bone differentiation. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200040567-A |
| priorityDate | 2012-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 407.