abstract |
A compound of formula I: or a pharmaceutically acceptable salt thereof Wherein R 1 is optionally substituted thiadiazolyl and R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and R 8 are as defined herein. P2X 3 and / or P2X 2/3 and a method for preparing the compounds and methods of using the compounds for the treatment of diseases which are associated with receptor antagonists are also disclosed. |