http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101344605-B1
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0008 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-002 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-26 |
filingDate | 2008-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2013-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101344605-B1 |
titleOfInvention | Enantioselective Enzymatic Reduction Method of Hydroxyketo Compounds |
abstract | In the enantioselective enzymatic reduction method of hydroxyketone of general formula (I), to obtain chiral diol of general formula (II),n n n n n n n n Wherein R 1 = C 1 -C 6 alkyl and R 2 = —Cl, —CN, —OH, —H or C 1 -C 6 alkyl,n n n n n n n n Wherein R 1 and R 2 have the same meaning as in formula (I),n n n The hydroxyketone is reduced to oxidoreductase in the presence of NADH or NADPH as cofactor, whereinn n n a) the hydroxy ketone is provided to the reaction at a concentration of ≧ 50 g / l,n n n b) The oxidized cofactor NAD or NADP formed is continuously regenerated by oxidation of a secondary alcohol of the general formula R X R Y CHOH, wherein R X , R Y independently represents hydrogen, branched or unbranched C 1 -C 8 -alkyl, C total ≥ 3,n n n c) reduction of the hydroxy ketone and oxidation of the secondary alcohol are catalyzed by the same oxidoreductase. |
priorityDate | 2005-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 521.