http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101343668-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-15 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4015 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 |
| filingDate | 2011-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2013-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101343668-B1 |
| titleOfInvention | Screening method of drug for treating metabolic syndrome using 3-indolinone derivative |
| abstract | The present invention provides a screening kit of a metabolic syndrome therapeutic drug comprising a compound that specifically stains only lipids, and a method for screening a metabolic syndrome therapeutic drug using the same. The 3-indolinone derivatives or salts thereof represented by Formula 1 or 2 of the present invention have a characteristic of staining only adipose tissue only with high sensitivity, thereby measuring the amount of adipose tissue by optical method by measuring the fluorescence intensity generated therefrom. You can check it. Since this method can be performed without surgery or tissue extraction, it can prevent unnecessary sacrifice of experimental animals, and the movement, production and disappearance of adipose tissue in vivo can be observed for a long time. Therefore, the screening kit comprising a 3-indolinone derivative represented by Formula 1 or 2 of the present invention or a salt thereof may be usefully used for the development of a drug for treating metabolic syndrome. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11690824-B2 |
| priorityDate | 2011-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 246.