| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-7014 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y111-01007
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7105 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 |
| filingDate |
2011-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2013-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2013-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-101341316-B1 |
| titleOfInvention |
Antiangiogenic composition comprising a peroxidase inhibitor as an active ingredient |
| abstract |
The present invention relates to a composition for inhibiting angiogenesis comprising a peroxidasin inhibitor as an active ingredient, more specifically, an inhibitor of the expression of a peroxidasin gene or an activity inhibitor of a peroxidasin protein. After treating the pharmaceutical composition and the test substance for inhibiting angiogenesis, comprising: analyzing the expression of peroxidasin (peroxidasin) gene or protein activity; And it relates to a method for screening angiogenesis inhibitors comprising the step of comparing the expression of the peroxidasin gene (peroxidasin) gene or the activity of the test material untreated test substance. Therefore, inhibitors that inhibit the expression of peroxidasin or protein activity according to the present invention can effectively inhibit cell migration, cell proliferation and angiogenesis of endothelial cells, and thus various diseases or disorders caused by abnormal control of angiogenesis. There is an effect that can be usefully used to effectively prevent or treat a condition. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017123021-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101928488-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20210025506-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10836995-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102506210-B1 |
| priorityDate |
2011-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |