http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101336678-B1

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-472
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-24
filingDate 2006-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2013-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-101336678-B1
titleOfInvention Cyclohexylamine Isoquinolone Derivatives as Rｈｏ-Kinase Inhibitors
abstract The present invention provides a 6-cyclohexylamine-substituted isoquinolone derivative of formula (I) or an isoquinoline derivative of formula (Ia) useful for the treatment and / or prevention of diseases associated with Rho-kinase mediated phosphorylation of Rho-kinase and / or myosin light chain phosphatase. And compositions containing such compounds.n n n Formula In n n n n n n n Ian n n n n n n n In Chemical Formulas I and Ia,n n n R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 6 ′, R 7 , R 8 , R 9 , n and L are as defined herein.n n n Rho-kinase-mediated phosphorylation of isoquinolone derivatives, isoquinoline derivatives, Rho-kinase, myosin light chain phosphatase
priorityDate 2005-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 62.