abstract |
The present application is a poly (ethylene glycol) / poly (peptide) block copolymer having a molecular weight of 1,000 Daltons to 50,000 Daltons, consisting of a poly (ethylene glycol) having a molecular weight of 500 Daltons to 5000 Daltons and a hydrophobic poly (peptide) having a molecular weight of 300 Daltons to 10,000 Daltons. Reacts to chitosan and relates to chitosan-graft- (polypeptide-poly (ethyleneglycol)) (CS-g- (PP-PEG)) having a molecular weight of 5,000 Daltons to 2,000,000 Daltons. The aqueous polymer solution is characterized in that the sol-gel transition temperature can be adjusted according to the pH and temperature above a certain concentration, and is intended for application as a drug delivery system, three-dimensional cell culture and tissue engineering. |