http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101334779-B1

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-64
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K9-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64
filingDate 2012-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2013-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-101334779-B1
titleOfInvention Reversible Fluorescent Switch for High-Contrast Biological Imaging Based on Uniformly Sized Silica Nanoparticles
abstract The present invention relates to a reversible fluorescence switch for high contrast biometric imaging based on uniformly sized silica nanoparticles. In the silica nanoparticles into which the fluorescent material and the photochromic material according to the present invention are introduced, the fluorescent material and the photochromic material are evenly formed on the inside and the surface of the silica nanoparticles using a photochromic material and a fluorescent material having a silane group introduced at one end thereof. It can be switched on-off with high contrast by maximizing FRET and improving biocompatibility by converting all amine groups on the surface of silica nanoparticles into carboxylate, which can be usefully used as a diagnostic reagent in biological imaging systems. Can be.
priorityDate 2011-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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