http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101328591-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0819 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2200-0668 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0829 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B29C41-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B29C59-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502707 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502761 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B29C59-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-28 |
| filingDate | 2011-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2013-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-101328591-B1 |
| titleOfInvention | Polymer substrate for single cell capture, preparation method thereof, and cell capture system comprising the same |
| abstract | A polymer substrate for single cell capture, a method of manufacturing the same, and a cell capture system including the same are provided. Single cell capture polymer substrate according to the present invention comprises the steps of applying a first polymer layer on a silicon substrate formed with one or more hemispherical grooves; After curing the first polymer layer, separating the first polymer layer from the silicon substrate to produce a first polymer mold with one or more hemispheres protruding upward; Pressing the first polymer mold with a second polymer layer to transfer the hemispherical shape of the first polymer mold to the second polymer layer in an intaglio form; And reducing the thickness of the second polymer layer to which the hemispherical shape has been transferred, thereby opening the lower hemisphere. As a hole-formed structure, cells can be effectively separated from the solution by flowing the cells from the cell-containing solution into the hemisphere and trapping them. In addition, the hemispherical hole according to the present invention is capable of capturing and preserving a cell as it is, and has an advantage of reducing cell deformation compared to a conventional single cell capture chip. Furthermore, since the polymer-based cell capture substrate is manufactured by using the silicon substrate template, the manufacturing process is simple, large-area manufacturing, and economical. |
| priorityDate | 2011-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.