| abstract |
The present invention relates to a composition for treating, improving or preventing arthritis, comprising a honey leaf extract as an active ingredient. The honey leaf extract is not only cytotoxic, but also confirmed the inhibitory activity of the cytokine (cytokine) mRNA associated with inflammation, the amount of NO secretion and COX-2 enzyme causing inflammation, effectively inhibiting inflammation In addition, it was confirmed through animal experiments that can effectively inhibit the differentiation of osteoclasts with respect to arthritis, and the pharmaceutical composition or arthritis prevention or improvement effect of the arthritis treatment or prevention comprising the same as an active ingredient It can be applied to such a food composition. |