abstract |
The present invention provides a compound of formula (I), which is a glycine transporter 1 (hereinafter referred to as GlyT-1) inhibitor, and thus has a cognitive disorder associated with schizophrenia, ADHD (attention deficit hyperactivity disorder), MCI (mild) Cognitive impairment), and the like, which is useful for the treatment of diseases treatable by inhibition of GlyT1: (I) . Also provided are pharmaceutical compositions containing such compounds and methods of making such compounds. |