| abstract |
The present invention relates to compounds of formula (I)n n n <Formula I>n n n n n n n n Wheren n n n is 0, 1, 2 or 3;n n n X 1 , X 2 , X 3 , X 4 , Z 1 , Z 2 , Z 3 , Z 4 and Z 5 represent a hydrogen atom or a specific specific substituent;n n n W represents a fused bicyclic group of formula (a) linked to a nitrogen atom at position 1, 2, 3 or 4,n n n <Formula a>n n n n n n n n A represents a 5- to 7-membered heterocycle comprising 1 to 3 heteroatoms selected from O, S and N.n n n The compound is a ligand of the TRPV 1 vanilloid receptor useful for treating pain and inflammation.n n n TRPV1 vanilloid receptor, pain, inflammation |