http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101275267-B1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7fd15d8ebb22202b5cfe2b109cd922c5 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-154 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57449 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 |
filingDate | 2013-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b49677a845243272aecf9a10c829533e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72001d48d9a9759215dd8fbcddb04f91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ada52f30e40ed58b54f9c1d73bb1348 |
publicationDate | 2013-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-101275267-B1 |
titleOfInvention | Composition for diagnosing metastatic characteristics of ovarian cancer using cpg methylation status in promoter region of ca9 gene and uses thereof |
abstract | PURPOSE: A composition for diagnosing metastatic ovarian cancer using CpG methylation change of a CA9(carbonic anhydrase 9) gene promoter, and a use thereof are provided to measure methylation levels of a certain gene promoter site of genome DNA collected from a patient's sample by MSP(Methylation-Specific PCR), to quickly diagnose the risk of metastasis, and to develop a convenient diagnostic kit. CONSTITUTION: A composition for diagnosing ovarian cancer metastasis or predicting the risk of metastasis contains an agent which measures methylation levels of a CpG site of a CA9 gene promoter. The agent contains: a compound which changes non-methylated cytosine or a methylation-sensitive restriction enzyme; a primer which is specific to a methylated sequence of an AGR2 gene promoter; and a primer which is specific to a non-methylated sequence of the AGR2 gene promoter. A method for providing information for diagnosing ovarian cancer metastasis or predicting the risk of metastasis comprises: a step of measuring the methylation level of the CpG site of the CA9 gene promoter from a patient's sample; and a step of comparing methylation levels with a control group. |
priorityDate | 2013-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 75.