| abstract |
Salts and crystals of 1-cyclopropylmethyl-4- [2- (3,3,5,5-tetramethylcyclohexyl) phenyl] piperazine have excellent cell adhesion inhibitory effect and cell invasion inhibitory effect, and inflammatory bowel Treatment or prevention of various inflammatory and autoimmune diseases caused by adhesion and infiltration of leukocytes such as diseases (especially ulcerative colitis or Crohn's disease), irritable bowel syndrome, rheumatoid arthritis, psoriasis, multiple sclerosis, asthma, atopic dermatitis Useful as |